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1

Selection of Evodiamine as a Novel Topoisomerase I Inhibitor by Structure-Based Virtual Screening and Hit Optimization of Evodiamine Derivatives as Antitumor Agents

Dong, Guoqiang, Sheng, Chunquan, Wang, Shengzheng, Miao, Zhenyuan, Yao, Jianzhong, Zhang, Wannian

Journal:

Journal of Medicinal Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 4.67 MB

english, 2010

2

Continuous lumbar spine rhythms during level walking, stair climbing and trunk flexion in people with and without lumbar disc herniation

Kuai, Shengzheng, Guan, Xinyu, Zhou, Wenyu, Zhang, Rui, Ji, Run, Liao, Zhenhua, Guo, Daiqi, Liu, Weiqiang, Wang, Daping

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 839 KB

english, 2018

3

Sign consistency for the linear programming discriminant rule

Zhang, Zhen, Wang, Shengzheng, Bian, Wei

Journal:

Pattern Recognition

Année:

2020

Langue:

english

Fichier:

PDF, 932 KB

english, 2020

4

Total synthesis and structure–activity relationships of caspofungin-like macrocyclic antifungal lipopeptides

Jianzhong Yao, Hongming Liu, Ting Zhou, Hai Chen, Zhenyuan Miao, Guoqiang Dong, Shengzheng Wang, Chunquan Sheng, Wannian Zhang

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 1.31 MB

english, 2012

5

New irrigation methods sustain malaria control in Sichuan Province, China

Liu Qunhua, Kang Xin, Chao Changzhi, Feng Shengzheng, Li Yan, He Rongzhi, Zhang Zhihua, G. Gibson, Kang Wenmin

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 77 KB

english, 2004

6

Discovery of highly potent triazole antifungal derivatives by heterocycle-benzene bioisosteric replacement

Jiang, Zhigan, Wang, Yan, Wang, Wenya, Wang, Shengzheng, Xu, Bo, Fan, Guorong, Dong, Guoqiang, Liu, Yang, Yao, Jianzhong, Miao, Zhenyuan, Zhang, Wannian, Sheng, Chunquan

Journal:

European Journal of Medicinal Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 653 KB

english, 2013

7

Scaffold Diversity Inspired by Natural Product Evodiamine: Discovery of Highly Potent and Multi-targeting Antitumor Agents

Wang, Shengzheng, Fang, Kun, Dong, Guoqiang, Chen, Shuqiang, Liu, Na, Miao, Zhenyuan, Yao, Jianzhong, Li, Jian, Zhang, Wannian, Sheng, Chunquan

Journal:

Journal of Medicinal Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 2.18 MB

english, 2015

8

Enhanced removal of veterinary antibiotic from wastewater by photoelectroactive biofilm of purple anoxygenic phototroph through photosynthetic electron uptake

Sun, Jian, Yang, Ping, Huang, Shengzheng, Li, Nan, Zhang, Yaping, Yuan, Yong, Lu, Xingwen

Journal:

Science of The Total Environment

Année:

2020

Langue:

english

Fichier:

PDF, 4.04 MB

english, 2020

9

ChemInform Abstract: Design and Synthesis of Antifungal Benzoheterocyclic Derivatives by Scaffold Hopping.

Chunquan Sheng, Xiaoying Che, Wenya Wang, Shengzheng Wang, Yongbing Cao, Jianzhong Yao, Zhenyuan Miao, Wannian Zhang

Journal:

Année:

2011

Fichier:

PDF, 31 KB

2011

10

Improved Model of Lanosterol 14α-Demethylase by Ligand-Supported Homology Modeling: Validation by Virtual Screening and Azole Optimization

Chunquan Sheng, Wenya Wang, Xiaoying Che, Guoqiang Dong, Shengzheng Wang, Haitao Ji, Zhenyuan Miao, Jianzhong Yao, Wannian Zhang

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 454 KB

english, 2010

11

Structure-based rational design, synthesis and antifungal activity of oxime-containing azole derivatives

Yulan Xu, Chunquan Sheng, Wenya Wang, Xiaoying Che, Yongbing Cao, Guoqiang Dong, Shengzheng Wang, Haitao Ji, Zhenyuan Miao, Jianzhong Yao, Wannian Zhang

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2010

Langue:

english

Fichier:

PDF, 259 KB

english, 2010

12

Design, synthesis and antifungal activity of isosteric analogues of benzoheterocyclic N-myristoyltransferase inhibitors

Chunquan Sheng, Hui Xu, Wenya Wang, Yongbing Cao, Guoqiang Dong, Shengzheng Wang, Xiaoying Che, Haitao Ji, Zhenyuan Miao, Jianzhong Yao, Wannian Zhang

Journal:

European Journal of Medicinal Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 713 KB

english, 2010

13

Novel conformationally restricted triazole derivatives with potent antifungal activity

Wenya Wang, Shengzheng Wang, Yang Liu, Guoqiang Dong, Yongbing Cao, Zhenyuan Miao, Jianzhong Yao, Wannian Zhang, Chunquan Sheng

Journal:

European Journal of Medicinal Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 425 KB

english, 2010

14

Design and synthesis of antifungal benzoheterocyclic derivatives by scaffold hopping

Chunquan Sheng, Xiaoying Che, Wenya Wang, Shengzheng Wang, Yongbing Cao, Jianzhong Yao, Zhenyuan Miao, Wannian Zhang

Journal:

European Journal of Medicinal Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 501 KB

english, 2011

15

Synthesis and biological evaluation of novel 7-acyl homocamptothecins as Topoisomerase I inhibitors

Wenfeng Liu, Lingjian Zhu, Wei Guo, Chunlin Zhuang, Yongqiang Zhang, Chunquan Sheng, Pengfei Cheng, Jianzhong Yao, Wenya Wang, Guoqiang Dong, Shengzheng Wang, Zhenyuan Miao, Wannian Zhang

Journal:

European Journal of Medicinal Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 498 KB

english, 2011

16

Structure-Based Design, Synthesis, and Antifungal Activity of New Triazole Derivatives

Chunquan Sheng, Xiaoying Che, Wenya Wang, Shengzheng Wang, Yongbing Cao, Jianzhong Yao, Zhenyuan Miao, Wannian Zhang

Journal:

Chemical Biology & Drug Design

Année:

2011

Langue:

english

Fichier:

PDF, 186 KB

english, 2011

17

Design and synthesis of novel triazole antifungal derivatives by structure-based bioisosterism

Chunquan Sheng, Xiaoying Che, Wenya Wang, Shengzheng Wang, Yongbing Cao, Zhenyuan Miao, Jianzhong Yao, Wannian Zhang

Journal:

European Journal of Medicinal Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 440 KB

english, 2011

18

Synthesis and biological evaluation of thio-benzodiazepines as novel small molecule inhibitors of the p53–MDM2 protein–protein interaction

Chunlin Zhuang, Zhenyuan Miao, Lingjian Zhu, Yongqiang Zhang, Zizhao Guo, Jianzhong Yao, Guoqiang Dong, Shengzheng Wang, Yang Liu, Hai Chen, Chunquan Sheng, Wannian Zhang

Journal:

European Journal of Medicinal Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 545 KB

english, 2011

19

Design, synthesis and structure–activity relationships of new triazole derivatives containing N-substituted phenoxypropylamino side chains

Shengzheng Wang, Gang Jin, Wenya Wang, Lingjian Zhu, Yongqiang Zhang, Guoqiang Dong, Yang Liu, Chunlin Zhuang, Zhenyuan Miao, Jianzhong Yao, Wannian Zhang, Chunquan Sheng

Journal:

European Journal of Medicinal Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 451 KB

english, 2012

20

New Tricks for an Old Natural Product: Discovery of Highly Potent Evodiamine Derivatives as Novel Antitumor Agents by Systemic Structure–Activity Relationship Analysis and Biological Evaluations

Dong, Guoqiang, Wang, Shengzheng, Miao, Zhenyuan, Yao, Jianzhong, Zhang, Yongqiang, Guo, Zizhao, Zhang, Wannian, Sheng, Chunquan

Journal:

Journal of Medicinal Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2012

21

Discovery, Synthesis, and Biological Evaluation of Orally Active Pyrrolidone Derivatives as Novel Inhibitors of p53–MDM2 Protein–Protein Interaction

Zhuang, Chunlin, Miao, Zhenyuan, Zhu, Lingjian, Dong, Guoqiang, Guo, Zizhao, Wang, Shengzheng, Zhang, Yongqiang, Wu, Yuelin, Yao, Jianzhong, Sheng, Chunquan, Zhang, Wannian

Journal:

Journal of Medicinal Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 1.47 MB

english, 2012

22

Synthesis and preliminary bioevaluation of novel E-ring modified acetal analog of camptothecin as cytotoxic agents

Zhu, Lingjian, Zhuang, Chunlin, Lei, Ning, Guo, Zizhao, Sheng, Chunquan, Dong, Guoqiang, Wang, Shengzheng, Zhang, Yongqiang, Yao, Jianzhong, Miao, Zhenyuan, Zhang, Wannian

Journal:

European Journal of Medicinal Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2012

23

Structure–activity relationship and antitumor activity of thio-benzodiazepines as p53–MDM2 protein–protein interaction inhibitors

Guo, Zizhao, Zhuang, Chunlin, Zhu, Lingjian, Zhang, Yongqiang, Yao, Jianzhong, Dong, Guoqiang, Wang, Shengzheng, Liu, Yang, Chen, Hai, Sheng, Chunquan, Miao, Zhenyuan, Zhang, Wannian

Journal:

European Journal of Medicinal Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 392 KB

english, 2012

24

Facile Construction of Structurally Diverse Thiazolidinedione-Derived Compounds via Divergent Stereoselective Cascade Organocatalysis and Their Biological Exploratory Studies

Zhang, Yongqiang, Wang, Shengzheng, Wu, Shanchao, Zhu, Shiping, Dong, Guoqiang, Miao, Zhenyuan, Yao, Jianzhong, Zhang, Wannian, Sheng, Chunquan, Wang, Wei

Journal:

ACS Combinatorial Science

Année:

2013

Langue:

english

Fichier:

PDF, 922 KB

english, 2013

25

Asymmetric Synthesis of Chiral Dihydrothiopyrans via an Organocatalytic Enantioselective Formal Thio [3 + 3] Cycloaddition Reaction with Binucleophilic Bisketone Thioethers

Wang, Shengzheng, Zhang, Yongqiang, Dong, Guoqiang, Wu, Shanchao, Zhu, Shiping, Miao, Zhenyuan, Yao, Jianzhong, Li, Hao, Li, Jian, Zhang, Wannian, Sheng, Chunquan, Wang, Wei

Journal:

Organic Letters

Année:

2013

Langue:

english

Fichier:

PDF, 467 KB

english, 2013

26

Facile Assembly of Chiral Tetrahydrothiopyrans Containing Four Consecutive Stereocenters via an Organocatalytic Enantioselective Michael–Michael Cascade

Wang, Shengzheng, Zhang, Yongqiang, Dong, Guoqiang, Wu, Shanchao, Fang, Kun, Li, Zhengang, Miao, Zhenyuan, Yao, Jianzhong, Li, Hao, Li, Jian, Zhang, Wannian, Wang, Wei, Sheng, Chunquan

Journal:

Organic Letters

Année:

2014

Langue:

english

Fichier:

PDF, 819 KB

english, 2014

27

Design, synthesis and antifungal activity of novel triazole derivatives containing substituted 1,2,3-triazole-piperdine side chains

Jiang, Zhigan, Gu, Julin, Wang, Chen, Wang, Shengzheng, Liu, Na, Jiang, Yan, Dong, Guoqiang, Wang, Yan, Liu, Yang, Yao, Jianzhong, Miao, Zhenyuan, Zhang, Wannian, Sheng, Chunquan

Journal:

European Journal of Medicinal Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 3.60 MB

english, 2014

28

Novel Carboline Derivatives as Potent Antifungal Lead Compounds: Design, Synthesis, and Biological Evaluation

Wang, Shengzheng, Wang, Yan, Liu, Wei, Liu, Na, Zhang, Yongqiang, Dong, Guoqiang, Liu, Yang, Li, Zhengang, He, Xiaomeng, Miao, Zhenyuan, Yao, Jianzhong, Li, Jian, Zhang, Wannian, Sheng, Chunquan

Journal:

ACS Medicinal Chemistry Letters

Année:

2014

Langue:

english

Fichier:

PDF, 2.44 MB

english, 2014

29

Discovery of highly potent antifungal triazoles by structure-based lead fusion

Wang, Wenya, Wang, Shengzheng, Dong, Guoqiang, Liu, Yang, Guo, Zizhao, Miao, Zhenyuan, Yao, Jianzhong, Zhang, Wannian, Sheng, Chunquan

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 213 KB

english, 2011

30

Asymmetric Synthesis, Antifungal Activity and Molecular Modeling of Iodiconazole Isomers

Zhang, Yongqiang, Wang, Shengzheng, Miao, Zhenyuan, Yao, Jianzhong, Zhang, Wannian, Sheng, Chunquan

Journal:

Chinese Journal of Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 748 KB

english, 2013

31

From Antidiabetic to Antifungal: Discovery of Highly Potent Triazole-Thiazolidinedione Hybrids as Novel Antifungal Agents

Wu, Shanchao, Zhang, Yongqiang, He, Xiaomeng, Che, Xiaoying, Wang, Shengzheng, Liu, Yang, Jiang, Yan, Liu, Na, Dong, Guoqiang, Yao, Jianzhong, Miao, Zhenyuan, Wang, Yan, Zhang, Wannian, Sheng, Chunqua

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 472 KB

english, 2014

32

Inside Cover: From Antidiabetic to Antifungal: Discovery of Highly Potent Triazole-Thiazolidinedione Hybrids as Novel Antifungal Agents (ChemMedChem 12/2014)

Wu, Shanchao, Zhang, Yongqiang, He, Xiaomeng, Che, Xiaoying, Wang, Shengzheng, Liu, Yang, Jiang, Yan, Liu, Na, Dong, Guoqiang, Yao, Jianzhong, Miao, Zhenyuan, Wang, Yan, Zhang, Wannian, Sheng, Chunqua

Journal:

Année:

2014

Fichier:

PDF, 1.11 MB

2014

33

Divergent Cascade Construction of Skeletally Diverse “Privileged” Pyrazole-Derived Molecular Architectures

Zhang, Yongqiang, Wu, Shanchao, Wang, Shengzheng, Fang, Kun, Dong, Guoqiang, Liu, Na, Miao, Zhenyuan, Yao, Jianzhong, Li, Jian, Zhang, Wannian, Sheng, Chunquan, Wang, Wei

Journal:

European Journal of Organic Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 2.05 MB

english, 2015

34

Prosthetic Left Renocaval Bypass for Posterior Nutcracker Syndrome

Zhang, Xuepei, Wang, Shengzheng, Wei, Jinxing

Journal:

Indian Journal of Surgery

Année:

2015

Langue:

english

Fichier:

PDF, 264 KB

english, 2015

35

Effects of diagnostic ultrasound-targeted microbubble destruction on the homing ability of bone marrow stromal cells to the kidney parenchyma

Wang, Gong, Zhang, Qian, Zhuo, Zhongxiong, Wu, Shengzheng, Liu, Zheng, Xia, Hongmei, Tan, Kaibin, Zou, Linru, Gan, Ling, Gao, Yunhua

Journal:

European Radiology

Année:

2016

Langue:

english

Fichier:

PDF, 8.30 MB

english, 2016

36

Enhanced Homing of CXCR-4 Modified Bone Marrow–Derived Mesenchymal Stem Cells to Acute Kidney Injury Tissues by Micro-Bubble–Mediated Ultrasound Exposure

Wang, Gong, Zhang, Qian, Zhuo, Zhongxiong, Wu, Shengzheng, Xu, Yali, Zou, Linru, Gan, Ling, Tan, Kaibin, Xia, Hongmei, Liu, Zheng, Gao, Yunhua

Journal:

Ultrasound in Medicine & Biology

Année:

2016

Langue:

english

Fichier:

PDF, 1.58 MB

english, 2016

37

Meeting Organocatalysis with Drug Discovery: Asymmetric Synthesis of 3,3′-Spirooxindoles Fused with Tetrahydrothiopyrans as Novel p53-MDM2 Inhibitors

Wang, Shengzheng, Jiang, Yan, Wu, Shanchao, Dong, Guoqiang, Miao, Zhenyuan, Zhang, Wannian, Sheng, Chunquan

Journal:

Organic Letters

Année:

2016

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2016

38

SPIE Proceedings [SPIE International Symposium on Optical Science and Technology - San Diego, CA (Sunday 30 July 2000)] Applications of Digital Image Processing XXIII - Imaging system of the Space Solar Telescope

Zhang, Bin, Jin, Shengzheng, Tescher, Andrew G.

Année:

2000

Langue:

english

Fichier:

PDF, 374 KB

english, 2000

39

Facile construction of pyrrolo[1,2-b]isoquinolin-10(5H)-ones via a redox-amination–aromatization–Friedel–Crafts acylation cascade reaction and discovery of novel topoisomerase inhibitors

Wu, Shanchao, Liu, Na, Dong, Guoqiang, Ma, Lin, Wang, Shengzheng, Shi, Wencai, Fang, Kun, Chen, Shuqiang, Li, Jian, Zhang, Wannian, Sheng, Chunquan, Wang, Wei

Journal:

Chemical Communications

Année:

2016

Langue:

english

Fichier:

PDF, 1.24 MB

english, 2016

40

A robust coherent point drift approach based on rotation invariant shape context

Zhang, Pengpeng, Qiao, Yu, Wang, Shengzheng, Yang, Jie, Zhu, Yuemin

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 3.41 MB

english, 2016

41

Organocatalytic Asymmetric Synthesis of Spiro−tetrahydrothiophene Oxindoles Bearing Four Contiguous Stereocenters by One-Pot Michael-Henry-Cascade-Rearrangement Reactions

Wang, Shengzheng, Guo, Zhongjie, Chen, Shuqiang, Jiang, Yan, Zhang, Fan, Liu, Xueying, Chen, Weiping, Sheng, Chunquan

Journal:

Chemistry - A European Journal

Année:

2017

Langue:

english

Fichier:

PDF, 2.19 MB

english, 2017

42

Organocatalytic Asymmetric Synthesis of Spiro-Tetrahydrothiophene Oxindoles Bearing Four Contiguous Stereocenters by One-Pot Michael-Henry-Cascade-Rearrangement Reactions

Wang, Shengzheng, Guo, Zhongjie, Chen, Shuqiang, Jiang, Yan, Zhang, Fan, Liu, Xueying, Chen, Weiping, Sheng, Chunquan

Journal:

Chemistry - A European Journal

Année:

2017

Fichier:

PDF, 5.47 MB

2017

43

Synthesis of Spiro−tetrahydrothiopyran−oxindoles by Michael–aldol Cascade Reactions: Discovery of Potential P53-MDM2 Inhibitors with Good Antitumor Activity

Wang, Shengzheng, Chen, Shuqiang, Guo, Zhongjie, He, Shipeng, Zhang, Fan, Liu, Xueying, chen, weiping, Zhang, Shengyong, Sheng, Chunquan

Journal:

Organic & Biomolecular Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 1.02 MB

english, 2017

44

Thyroid nodules in centenarians: prevalence and relationship to lifestyle characteristics and dietary habits

Yao, Yao, Chen, Xianghui, Wu, Shengzheng, Liang, Guo, Zhang, Hao, Zhu, Qiao, Tang, Jie, Luan, Fuxin, Zhao, Yali, Lv, Faqin, He, Yao

Journal:

Clinical Interventions in Aging

Année:

2018

Langue:

english

Fichier:

PDF, 864 KB

english, 2018

45

The Effect of Lumbar Disc Herniation on Musculoskeletal Loadings in the Spinal Region During Level Walking and Stair Climbing

Kuai, Shengzheng, Liao, Zhenhua, Zhou, Wenyu, Guan, Xinyu, Ji, Run, Zhang, Rui, Guo, Daiqi, Liu, Weiqiang

Journal:

Medical Science Monitor

Année:

2017

Langue:

english

Fichier:

PDF, 1.28 MB

english, 2017

46

Resveratrol protects against isoproterenol induced myocardial infarction in rats through VEGF-B/AMPK/eNOS/NO signaling pathway

Feng, Lifeng, Ren, Jiling, Li, Yafei, Yang, Guifang, Kang, Licheng, Zhang, Shengzheng, Ma, Changzhen, Li, Jing, Liu, Jie, Yang, Liang, Qi, Zhi

Journal:

Free Radical Research

Année:

2018

Langue:

english

Fichier:

PDF, 5.55 MB

english, 2018

47

Design, Synthesis and Biological Evaluation of Novel Antitumor Spiro-dihydrothiopyran–oxindole Derivatives

Liu, Wei, Chen, Shuqiang, Zhang, Fan, He, Shipeng, Wang, Shengzheng, Sheng, Chunquan

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2019

Langue:

english

Fichier:

PDF, 1.39 MB

english, 2019

48

Preoperative predictors of early death risk in bladder cancer patients treated with robot‐assisted radical cystectomy

Zhu, Zhaowei, Wang, Xiaojing, Wang, Jiange, Wang, Shengzheng, Fan, Yafeng, Fu, Tianlong, Cao, Songqiang, Zhang, Xuepei

Journal:

Cancer Medicine

Année:

2019

Langue:

english

Fichier:

PDF, 289 KB

english, 2019

49

Preoperative predictors of early death risk in bladder cancer patients treated with robot‐assisted radical cystectomy

Zhu, Zhaowei, Wang, Xiaojing, Wang, Jiange, Wang, Shengzheng, Fan, Yafeng, Fu, Tianlong, Cao, Songqiang, Zhang, Xuepei

Journal:

Cancer Medicine

Année:

2019

Fichier:

PDF, 289 KB

2019

50

[IEEE 2019 41st Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC) - Berlin, Germany (2019.7.23-2019.7.27)] 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) - How Height and Weight of Patients with Spinal Cord Injury Affect the Spring Locations of Unpowered Energy-stored Exoskeleton

Guan, Xinyu, Kuai, Shengzheng, Song, Liang, Li, Chong, Liu, Weifeng, Liu, Yali, Ji, Linhong, Wang, Rencheng, Zhang, Zhiqiang

Année:

2019

Langue:

english

Fichier:

PDF, 932 KB

english, 2019